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Prospective Comparison of a Cohort with Asympt Carotid Bruit & A Population-Based Cohort Without Carotid Bruit
Stroke 21:984-988, Wiebers,D.O.,et al, 1990
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Article Abstract
This study is a prospective analysis of the predictive value of diffuse and localized carotid bruit.Patients with asymptomatic carotid bruits are compared with a population-based age-and sex-matched control group known not to have carotid bruit,in regard to subsequent transient ischemic attack,stroke,and death.Each person was followed until death or for 5 years.Among the 566 patients with asymptomatic carotid bruit,the annual stroke rate given survival was 1.5%/yr or 7.5%at 5 years by actuarial analysis.The annual stroke rate given survival for the 428 patients in the population-based cohort was 0.5%/yr or 2.4%at 5 years.Patients with localized carotid bruit were not significantly different from those with diffuse carotid bruits in regard to subsequent cerebral ischemic events(p= 0.11).These data indicate that patients with asymptomatic diffuse or localized carotid bruit are approximately three times more likely to have ischemic stroke than an age-and sex-matched population sample known not to have carotid bruit.
 
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bruit
bruit,asymptomatic
carotid artery disease
carotid artery disease,asymptomatic
carotid artery disease,noninvasive evaluation of
cerebrovascular accident
cerebrovascular disease,risk factors in
epidemiology of neurology
prognosis
transient ischemic attack

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